Atc Core Bonding Manual Transfer

(Article 8.25.1). = area of core of spirally reinforced compres- sion member measured to the outside diam- eter of the spiral, square inches (Article. 8.18.2.2.2); area of concrete section resist- ing shear, square inches (Article 8.16.6.9). = area of concrete section resisting shear transfer, square inches (Article 8.16.6.4.5).

Scheme for epothilone biosynthesis, focusing on thiazol(in)e formation by the NRPS cyclization domain. ( A) Epothilones ( Right) are large macrocycles with a thiazole-containing side chain (red), which are produced by a hybrid PKS-NRPS, EpoA-K. EpoA and EpoB are responsible for producing the thiazole side chain and have the following domains (–): KSy, ketosynthase-like domain; AT, acyltransferase domain; ER, enoyl reductase; and T, an acyl carrier protein. The NRPS EpoB domains include the following: A, adenylation domain; Cy, cyclization; Ox, a flavin-dependent oxidase domain; and T, a carrier protein domain (). The Ppant group of each T domain is represented as a squiggly line and residue numberings for the EpoA-T, and EpoBcy constructs are indicated.

( B) Proposed mechanisms for condensation and cyclodehydration. The EpoA-T domain and EpoB-T domains are represented as red and blue spheres, respectively. The epothilone biosynthetic gene cluster from Sorangium cellulosum is encoded by epoA-K (). EpoA, a polyketide synthase (PKS), and EpoB, a nonribosomal peptide synthetase (NRPS), are responsible for making the 2-methylthiazole functionality (–). Lirik Lagu Kaulah Ibuku there.